You can set a connection to a database either from the Profiling perspective or from the Integration perspective. The database connection you create is listed under the Metadata node in both perspectives. You can then use this connection in your data quality analyses and data integration Jobs.
However, fewer databases are supported for profiling data than those supported for integrating data, this is why the database list in the connection wizard is much longer in the Integration perspective. Also, in the Profiling perspective, the connections created on unsupported databases are labeled as Unsupported.
For further information about what databases are supported for profiling data, see the section about supported databases in the Talend Installation and Upgrade Guide.